13 Comments
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Steveo's avatar

Isn’t no dose response a huge red flag?

Sebastian Jensen's avatar

Not necessarily, it could be that the cognitive benefits saturate early, while the stimulatory effects do not.

Rothari's avatar

So basically, a single miligram of it? I am skeptical but also hopeful here. It might be good, taken rarely (once or twice a month maximally, avoiding tolerance development) for either 1) initiating the study or practice of something unfamiliar or 2) having to combine multiple methods to set up an environment/ecosystem that makes things possible 3)pushing through something especially difficult individually or 4)bundling cognitive tasks together

I'm not understanding the conclusion that few people get addicted from the gum itself. from the conclusion it seems like 2/5 very much DID get addicted from the gum itself?

https://pmc.ncbi.nlm.nih.gov/articles/PMC1939993/

Five never smokers used the nicotine gum daily. They had been using the nicotine gum for longer than the 429 ever smokers (median = 6 years vs 0.8 years, p = 0.004), and they had higher NDSS-gum Tolerance scores (median = 0.73 vs = -1.0, p = 0.03), a difference of 1.5 standard deviation units. Two never smokers had never used smokeless tobacco, both answered "extremely true" to: "I use nicotine gums because I am addicted to them", both "fully agreed" with: "after a few hours without chewing a nicotine gum, I feel an irresistible urge to chew one" and: "I am a prisoner of nicotine gum".

2/5 seems pretty high, a 40% addiction rate here.

Hopeful we get more studies on this. Any dosage of anything to literally improve IQ is an insanely outsized benefit. It warrants investigation then standardization. I won't be surprised if we figure something out in the future that's like ozempic and a strong-enough boost in cognition, on wider scales.

Donald Beane Jr's avatar

I am so sensitive to that shit.

Dronom!'s avatar

Is the IQ gain only while under the effects of nicotine

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Jul 24
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Aug 5
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Some User Name's avatar

Smoking is certainly bad. I don’t think nicotine by itself is harmful

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Aug 5
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Some User Name's avatar

Zyn is about as close as you can get

Jonathan Tweet's avatar

Thanks, that IQ gain seems to be a little bit exciting.

Norman Angleton's avatar

It's funny, i love the sensation of inhaling smoke from burning wood without any nicotine or THC required, so i might as well just become a smoker.

David Saum's avatar

What about improved reaction time?

Polandball's avatar

I could have asked ai this myself